80% of Adults Experience Adrenal Fatigue

Trust the lab that’s tested adrenal function for 1.4 million.

The adrenal glands, otherwise known as the “stress glands,” enable our bodies to cope with stress and survive. Shaped like two tiny pyramids, they sit atop the kidneys and from this central location mobilize the response to changes in our environment.

Whether stress comes from outside in the form of a natural disaster, or from within like the anxiety we experience before public speaking, it’s the adrenals’ job to help us adapt to the situation.

They accomplish this by secreting key hormones:

The primary stress hormone that fine-tunes our response to the stress of everyday living
One of the most abundant hormones in the body, and a precursor to estrogens and testosterone; also balances some of the negative effects of high cortisol
Epinephrine / Norepinephrine:
Neurotransmitters that mobilize the body’s natural “fight or flight” response in an emergency

Adrenals in balance produce adequate amounts of hormones to power us through the day. These hormones impact just about every process in the body, from energy production and immune activity to cellular maintenance and repair. They are key regulators of glucose, insulin and inflammation, and play a major role in bone and muscle building, mood and mental focus, stamina, sex drive and sleep cycles.

Adrenals that are out of balance can lead to:

High Cortisol

Results in insomnia, anxiety, sugar cravings, feeling tired but wired, increased belly fat & bone loss

Low Cortisol

Causes chronic fatigue, low energy, food and sugar cravings, poor exercise tolerance or recovery & low immune reserves


Out of balance adrenals can lead to high or low DHEA.

Learn More About Adrenal Imbalance

Recommended for Practitioners:

Webinar: HPA Axis Dysfunction

Recommended for Patients:

Webinar: The Thyroid & Adrenal Connection

Handbook: Adrenal Stress & Hormone Balance

Blog: 80% of Americans Experience Adrenal Fatigue

See the Profiles

To restore the vital balance of hormones, we first need a detailed, accurate measurement of hormone levels. Not just numbers, but an assessment that offers real meaning.

Hormone Profiles
View Adrenal Stress Profile

Diurnal Cortisol – Cx4

Adrenal Stress Profile – DS & Cx4 (Sample Report)

Adrenal Profile – A picture of adrenal hormone metabolism. 13 tests.

Intermediate Profile – An expanded look at sex steroid hormone metabolite levels, with a broader view of cortisol metabolism plus first-morning melatonin and BPA. 30 tests.

Advanced Profile – Our broadest view of sex steroid hormone metabolite levels and cortisol metabolism with full diurnal melatonin and BPA. 44 tests. (Sample Report)

Neurotransmitter Profiles

NeuroBasic Profile – GABA, Glu, DA, Epi, NE, 5-HT, PEA

NeuroIntermediate Profile – GABA, Glu, Gly, DA, Epi, NE, HIST, 5-HT, PEA

NeuroAdvanced Profile – GABA, Glu, Gly, DA, Epi, NE, HIST, 5-HT, PEA, DOPAC, HVA, 5-HIAA, NMN, VMA (Sample Report)

Saliva Hormones add-on – E2, Pg, T, DS, C

Urine Hormones add-on – E2, Pregnanediol, Allopregnanolone, Androstenedione, T, DHT, DHEA, 5α,3α-Androstanediol

Diurnal Cortisol add-on – Free Cortisol x 4, Free Cortisone x 4

Diurnal Cortisol & Melatonin add-on – Free Cortisol x 4, Free Cortisone x 4, Melatonin (MT6s) x 4

Diurnal Cortisol, Norepinephrine & Epinephrine add-on – Free Cortisol x 4, Free Cortisone x 4, NE x 4, Epi x 4

Diurnal Cortisol, Melatonin, Norepinephrine & Epinephrine add-on – Free Cortisol x 4, Free Cortisone x 4, Melatonin (MT6s) x 4, NE x 4, Epi x 4

Reference Information

ZRT Overview of Profiles

ZRT Test Directory & Abbreviations


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