The human microbiome maintains a close relationship with the endocrine system, indicating that these systems engage in meaningful communication and have a deep influence on each other. This is especially true in the case of estrogen and the gut microbiome. The estrobolome is the portion of the microbiome that influences estrogen metabolism. First defined in 2011, the estrobolome is the collection of all enteric bacteria capable of metabolizing estrogen. The estrobolome can impact endogenous estrogen metabolism by modulating the enterohepatic circulation of estrogens thus influencing plasma estrogen levels.…
Tags: estrobolome, gut microbes, hormones
