In my previous blog I discussed how the psychoactive component of marijuana (cannabis), mainly tetrahydrocannabinol (THC), can have a negative impact on your hormones. In this blog, I will delve into the world of cannabidiol (CBD), which has been making quite a buzz lately as a therapeutic panacea.Although they are derived from the same plant and have quite similar molecular structures, CBD is…

Tags: Endocannabinoid System, Immune System, Anxiety, Depression, Alzheimer's, Menopause, BDNF, Estrogen


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The Effects of Cannabis - Part 2: Cannibidiol

Here in the Pacific Northwest we love talking about the sun! We grumble about it being hidden away behind heavy rain clouds for months at a time in the winter; we delight in the first breakthrough rays in the spring, realizing our pagan longing for it, watching, as if for the first time, as everything around us wakes up from a deep slumber; we marvel at its delightful, almost intoxicating warmth…

Tags: Vitamin D, Sleep, Depression, PMS and PMDD, Metabolic Health, Melatonin, Blood Spot Testing


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The Connection Between Low Vitamin D and Sleep Disturbances

We are heading into the new year with a goal to strengthen our understanding of hormones, neurotransmitters, and heavy metals and the influence they have on our overall health and wellness. As we welcome 2019, we would like to take a moment to look back at our most popular blog posts from last year. Serotonin, or rather its deficiency, frequently…

Tags: Depression, Neurotransmitters, Stress, Mental Health, Heavy Metals, Sleep


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Looking Back: Popular Articles for Providers in 2018

The hypothalamus is directly innervated by neuronal systems that produce neurotransmitters, such as serotonin (5-HT), dopamine and norepinephrine (NE), that are involved in mood regulation and play various other roles in cognitive health. During the acute stress crisis, the mesolimbic dopaminergic reward system is stimulated to help maintain morale. However, during chronic stress or depression, the reward system is down-regulated by stress mediators, resulting in anhedonia.…

Tags: HPA Axis, Hormone Balance, Stress, Neurotransmitters, Depression


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Neurotransmitters, Mood & the Perception of Stress - Part 3

Glutamate (L-glutamic acid) and GABA (gamma-aminobutyric acid) are, respectively, the principal excitatory and inhibitory neurotransmitters in the CNS and play a significant role in HPA axis function and mood. These two amino acid-based neurotransmitters account for over 50% of the synapses in the brain, while the monoamines (serotonin, norepinephrine and dopamine) account for only about 5%.…

Tags: HPA Axis, Hormone Balance, Stress, Neurotransmitters, Depression


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Neurotransmitters, Mood & the Perception of Stress - Part 2

Why are Mitochondria Important? Mitochondria are organelles that are present in every cell of the body except red blood cells. Probably everyone reading this learned about these little guys in high sch­ool biology, where they were described as "the energy packs of the cells."About 20% of our body weight is mitochondria. This translates to about 250 quadrillion of these organelles. There are 37.2…

Tags: Neurotransmitters, Depression, Mental Health


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Mitochondria & Mental Health

When we talk about “stress,” or allostatic load, in terms of the perception of an event, we must realize that these “events” must first be translated into neurochemical signals before they trigger the HPA axis. Therefore, the sensitivity and outcome of translating these events (whether they are ongoing events, memories of past events, or stressful anticipation of unrealized events), is highly dependent upon signaling from other neurotransmitters.…

Tags: HPA Axis, Hormone Balance, Stress, Neurotransmitters, Depression


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Neurotransmitters, Mood & the Perception of Stress

Serotonin, or rather its deficiency, frequently steals the spotlight in conversations regarding depression. Initially discovered as a component of serum in 1948 to regulate vasoconstriction (serotonin = serum + tone), the role of serotonin in depressive disorders wasn't implied until a few years later. Since then, much effort has been dedicated by scientists and clinicians alike to understand the…

Tags: Menopause, Neurotransmitters, Depression


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The Impact of Hormones on Serotonin in Depression

Practical Takeaway: A recent study found the risk of depression with contraceptive use decreased with increasing age, and was highest in the youngest age group studied, namely teenagers aged 15-19, than in the women aged 20-34. These findings are from a new Danish study suggesting that hormonal contraception might increase risk of depression, and that previous studies may not have highlighted…

Tags: Fertility, Mental Health, Contraceptives, Neurotransmitters, Depression


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Do Hormonal Contraceptives Increase Risk of Depression?

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