In 2002 several large-scale clinical studies were published on the risks of breast cancer in postmenopausal women using conventional FDA-approved hormone therapy. These were the Women’s Health Initiative (WHI) and Million Women’s studies of women using FDA-approved estrogens and progestogens in the United States and Great Britain, respectively. Both studies came to the same conclusion – that…

Tags: Progesterone, Estrogen, Menopause, Breast Cancer, Brain Health


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Topical Progesterone, Not Synthetic Progestins or Oral Progesterone, Should Be Considered as a Companion for Estradiol Replacement Therapy

Having just entered my forties, my radar’s perked for solid information coming out of the research community on the perimenopausal transition. What can I do to make this 10 or so years of transition useful and even helpful to the future postmenopausal me? As women, we’re no strangers to functioning in some level of consistent discomfort – whether cycle-related, birth control related, pregnancy or…

Tags: Menopause, Cardiovascular Disease, Estrogen, Progesterone, Hormone Replacement Therapy, Metabolic Health, Cortisol


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A Perimenopausal Game Plan

Sometimes you look back and wonder where all the time went.Let’s see - in my twenties, the younger, sexier me had been to University and embarked on a career in medical research, and I’d been very active in my leisure time – including hiking and skiing every year in the Alps. I was too invested in my career and hobbies to have children and wanted to put that off until the right time.In my…

Tags: Menopause, Estrogen, Testosterone, Androgen, Hormone Replacement Therapy, Sleep, Stress


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The Younger, Sexy Me…...nopause!

ZRT is a company made up mostly of women. It’s not that we don’t have men working here, but 80% of our employees happen to be women. A combination of a company mostly of women, working in the health field, and having gone to medical school which tends to take away that filter that says “perhaps certain topics are off limits,” can lead to hilarious conversations like our one today on the favorite…

Tags: Menstrual Cycle Mapping, Estrogen, Progesterone, Saliva Testing, Blood Spot Testing, Menstruation


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Periods: The Miracle of Bleeding for 7 Days Without Dying

Delivery of the bioidentical hormones estradiol (E2), progesterone (Pg), and testosterone (T) through the skin as a cream or gel (topically) has become a mainstay of bioidentical hormone replacement therapy (BHRT) for women and men. A plethora of FDA-approved pharmaceuticals, compounded, and even over-the-counter topical BHRT products are available. The popularity of these products lies not only…

Tags: Bioidentical Hormones, Estrogen, Progesterone, Testosterone, Dried Urine Testing, Blood Spot Testing, Serum Testing, Saliva Testing


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Topical Delivery of Sex Steroid Hormones and Distribution in Different Body Fluids

When I turned 12, all of a sudden all of my friends were getting their periods, and I just couldn’t wait to get mine! I was so ready to join the ranks of glamorous women who had the privilege of being initiated into the menstruating club. I wanted to belong with them - everything about periods was synonymous with femininity for me at the time. I had to endure witnessing so many of my classmates…

Tags: PMS and PMDD, Estrogen, Progesterone, Menstruation, Menstrual Cycle Mapping


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Your Guide to PMDD: Causes and Treatment

In my previous blog I discussed how the psychoactive component of marijuana (cannabis), mainly tetrahydrocannabinol (THC), can have a negative impact on your hormones. In this blog, I will delve into the world of cannabidiol (CBD), which has been making quite a buzz lately as a therapeutic panacea.Although they are derived from the same plant and have quite similar molecular structures, CBD is…

Tags: Endocannabinoid System, Immune System, Anxiety, Depression, Alzheimer's, Menopause, BDNF, Estrogen


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The Effects of Cannabis - Part 2: Cannibidiol

A symbol of femininity for so many women, our hair demands attention. Both deeply personal and superficially public, changes in the looks of our hair can inspire a range of emotions, driving us to willingly partake in its cutting, straightening, curling, bleaching, darkening, or other aggressive chemical treatments. Hair is part of who we are and how we present ourselves to the world. This is why…

Tags: Stress, Menopause, Cortisol, Progesterone, Estrogen, PCOS, Thyroid Health, Vitamin D, Vitamin B12


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Understanding the Connection Between Hormones and Hair Loss

While cannabis is being legalized in more and more states, both the adverse and beneficial effects of its use are starting to be better understood. The active compound in cannabis, THC (tetrahydrocannabinol) is widely known to have effects on the brain, producing the “high” that many users are seeking. However, the other more adverse effects cannabis can have on the body are less widely known. In…

Tags: Endocannabinoid System, HPA Axis, HPT Axis, HPG Axis, Estrogen, Androgen, Adrenal and Cortisol, Thyroid Health


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The Effects of Cannabis on Your Hormones

Single nucleotide variations (SNVs – formerly single nucleotide polymorphisms, SNPs) are the most common genetic variations in individuals. Research shows that some SNVs can help predict an individual’s risk of developing certain diseases, such as breast cancer. Although future studies are necessary to further characterize the involvement of SNVs in the etiology of breast cancer, this blog will…

Tags: Breast Cancer, Estrogen, Estrogen Metabolism


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Genetic Sequence Variations and Breast Cancer Risk

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