While cannabis is being legalized in more and more states, both the adverse and beneficial effects of its use are starting to be better understood. The active compound in cannabis, THC (tetrahydrocannabinol) is widely known to have effects on the brain, producing the “high” that many users are seeking. However, the other more adverse effects cannabis can have on the body are less widely known. In…

Tags: Endocannabinoid System, HPA Axis, HPT Axis, HPG Axis, Estrogen, Androgen, Adrenal and Cortisol, Thyroid Health


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The Effects of Cannabis on Your Hormones

As we step into 2018, ready to deepen our understanding of the critical balance of hormones and neurotransmitters, as well as the role of elements in optimal health, we wanted to take a brief moment to reflect on the top stories of the past year. Following is a round-up of 2017's most popular posts for practitioners.…

Tags: Hormone Balance, Cancer, DHEA, Adrenal and Cortisol, ADD and ADHD


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Looking Back: Popular Articles for Providers in 2017

If you come by ZRT on Halloween you’re likely to be greeted by a witch, vampire, zombie or other nightcrawler. We take our decorations and dressing up seriously around here, and finding people in costume processing your labs or taking your calls is par for the course. Laughing aside (and let me tell you, some costumes are hilarious) those who live their lives by night – on the graveyard shift – can…

Tags: Sleep, Adrenal and Cortisol


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Cortisol Patterns For Graveyard (Shift) Workers

One of ZRT's most popular tests includes diurnal assessment of a patient's salivary cortisol levels. On the surface, these tests seem easy enough to interpret, but experienced clinicians know there can sometimes be pitfalls. Patients testing cortisol in a clinical setting may take undisclosed medications, live under stressful conditions, have inflammation, genetic variations, tumors, and diseases.…

Tags: Stress, Saliva Testing, Adrenal and Cortisol


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Avoiding 3 Common Interpretation Pitfalls for Salivary Cortisol Tests

The New York Times did a remarkable story the other day that ended with the line "When you hear hoofbeats, the chances are good that it's a horse…but we must also remember that sometimes the circus is in town." ZRT is apparently hosting the circus this year. At the odds of 3-8 individuals per million – ZRT has been instrumental in discovering two cases of pheochromocytoma tumors in the last…

Tags: Neurotransmitters, Stress, Cancer, Dried Urine Testing, Adrenal and Cortisol


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Pheochromocytoma - A Rare Condition Exposed by Neurotransmitter Testing

When clinicians measure salivary cortisol and DHEA (DHEA-S) to assess stress and HPA axis function, it is common to find DHEA levels below the reference range in a number of individuals. A common explanation for the depletion of DHEA and other hormones (e.g., progesterone, testosterone) due to chronic stress is the phenomenon known as "pregnenolone steal." The pregnenolone steal notion states that…

Tags: HPA Axis, Hormone Balance, Stress, Pregnenolone Steal, Adrenal and Cortisol


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Re-assessing the Notion of "Pregnenolone Steal"

Sometimes, when we endeavor to understand and describe complicated medical topics, there is a temptation to find a simple explanation to cut through the complexity. These explanations can help bridge the knowledge gap for a while, but as our knowledge grows, they lose some of their original usefulness (e.g., the notion of “good” and “bad” cholesterol). In some cases, those over-simplified…

Tags: Stress, HPA Axis, Hormone Balance, Adrenal and Cortisol


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Is It Adrenal Fatigue? Reassessing the Nomenclature of HPA Axis Dysfunction.

Providers routinely call ZRT for support in addressing low libido for their patients during the menopausal transition. Busy lifestyles, everyday stress, not enough or poor quality sleep and many other factors can all contribute to putting sex at the bottom of the to-do list, well after laundry, scrubbing the floor, and taking the dog to the vet. Low libido is a multidimensional issue that can have a…

Tags: Menopause, Estrogen Dominance, Adrenal and Cortisol


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How to Address Low Libido in Peri-Menopausal Patients

After beating cancer, Dr. Zembroski strives to prevent chronic disease in his patients. Hear his story."You have a 5-inch tumor in your chest" were the words spoken from a friend and radiologist as we both stared bewildered at my chest X-ray, following a host of side effects I'd been having for weeks. As I looked at the X-ray film in amazement, my thoughts quickly changed to frustration and anger…

Tags: Stress, Cancer, Adrenal and Cortisol


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How Stress Caused My Cancer

I wanted to share a few of the studies using saliva testing that were published in the literature in 2016. Just a hint, if you want to search for articles on saliva testing, use pubmed.gov and search saliva estradiol (or progesterone, testosterone etc.). Be aware that saliva hormone testing is so standard in the research world that rarely is it mentioned in the titles of the papers. Over 310…

Tags: Saliva Testing, Research, Estrogen, Testosterone, Progesterone, DHEA, Adrenal and Cortisol


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A Year of Saliva Testing in Research

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