According to the American Institute of Stress, 55% of people in the United States experience daily stress. Stress is, technically defined as the body's nonspecific response to any demand – pleasant or unpleasant – but more commonly perceived as a state of physical, mental, or emotional strain or tension. Chronic stress is especially prevalent in the workplace, with 83% of employees reporting daily work-related stress. However, statistics show that stress among students is also significant, common, and increases proportionally to a student’s progress through the educational system.…

Tags: Mental Health, Brain Health, Adrenal and Cortisol, Cortisol

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The Science of Stress: The Time-Dependent Multimodal Effects of Stress Hormones on Memory and Learning

​In part 1 of this blog post, we discussed the use of inositol for insulin resistance and related conditions. However, in the late 1990s and early 2000s researchers were largely focused on the effects of inositol on mood. A link between insulin resistance and depression has been established since, and may eventually provide one possible mechanism of action.…

Tags: Brain Health, Mental Health

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Inositol Supplementation – Recent Research in Mood Disorders: Part 2

SARS-CoV-2 has been circulating in the global population for over a year. According to Worldometer, at the time of this writing on March 2, 2021, 115 million people have been infected with the virus, 2.5 million have died, and 90 million have survived the infection to go on to have possible immunity. The immune response to the virus can range from asymptomatic to severe illness and death and has aroused fear and uncertainty around the world. For those who have been infected with SARS-CoV-2 and survived, some experience prolonged symptoms beyond recovery from the acute illness. Long COVID presents with ongoing symptoms of fatigue, post-exertional malaise (PEM), sleep issues, headaches, brain fog, cognitive issues, depression, anxiety, musculoskeletal pain, respiratory distress, and muscle weakness that extends far beyond initial recovery.…

Tags: Covid19, Brain Health, Neurotransmitters

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Long COVID and the Systemic Effects of Post-Viral Syndromes Part I: The Central Nervous System

Many children with Attention Deficit Hyperactivity Disorder (ADHD) struggle with fitting in and according to some experts, may receive as many as 20,000 negative messages by age 10 than their neurotypical peers. Little wonder then that many struggle with self-esteem and the belief that they are somehow broken.…

Tags: ADD and ADHD, Mental Health, Brain Health

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An Individualized Plan for Managing ADHD: Laboratory Testing & Lifestyle Modifications to Provide Symptom Relief

Last weekend I went whitewater rafting. A particularly turbulent patch of the rapids caught me off guard, when I tumbled off the raft into the water. It all happened so quickly. We hit a big rock, the raft turned vertical and I fell into the river. I was swept under and spat back out, my body tossed around like a tiny paper boat. I was gasping for air with the whitewater waves rising in front of me, crashing over…

Tags: Cortisol, Neurotransmitters, Brain Health, Mental Health, Heart Health, Stress

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Understanding a Broken Heart – The Physiology of Grief

In 2002 several large-scale clinical studies were published on the risks of breast cancer in postmenopausal women using conventional FDA-approved hormone therapy. These were the Women’s Health Initiative (WHI) and Million Women’s studies of women using FDA-approved estrogens and progestogens in the United States and Great Britain, respectively. Both studies came to the same conclusion – that…

Tags: Progesterone, Estrogen, Menopause, Breast Cancer, Brain Health

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Topical Progesterone, Not Synthetic Progestins or Oral Progesterone, Should Be Considered as a Companion for Estradiol Replacement Therapy

The incidence of Alzheimer’s disease is growing, now affecting 10% of people aged 65 and older. Two-thirds of Americans with Alzheimer’s Disease are women, and African Americans and Hispanics are more likely to be affected than white Americans. Low serum BDNF levels have been observed in patients with Alzheimer’s disease, begging the question: what is the connection between BDNF and Alzheimer’s…

Tags: BDNF, Alzheimer's, Depression, Brain Health, Metabolic Health, Cardiovascular Disease, Hormone Balance, Mental Health

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Exploring the Connection Between BDNF and Alzheimer's Disease

Theories abound on the origins of most major diseases, and many share one factor in common: inflammation. The biological consequences of inflammation are at the root of virtually every human malady from the common cold to cancer, allergies to arthritis, and headaches to heart disease. Yet inflammation is a natural, self-protective response of the body with the best of intentions. Inflammatory chemicals…

Tags: Alzheimer's, Brain Health

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Alzheimer’s:  A Biological Model of Prevention – Finally!  (Part 3)

The Alzheimer’s Association states that “the greatest known risk factor for Alzheimer’s is increasing age”, leading many to presume that a diagnosis is inescapable. Sadly, it is not only the uninformed expressing this cynicism; even highly-educated medical professionals have slumped in defeat. Of the leading causes of death in America, Alzheimer’s Disease stands alone as the only malady largely…

Tags: Alzheimer's, Brain Health, Heavy Metals

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Alzheimer’s: A Biological Model of Prevention – Finally! (Part 2)

News media are replete with alarming statistics about the current and future incidence of Alzheimer’s Disease. A recent CBS headline announced the latest data from the Centers for Disease Control predicting already troubling rates will “soar” in coming decades, with the number of cases potentially doubling by 2060 to almost 14 million Americans. With its impact going significantly beyond a…

Tags: Alzheimer's, Brain Health

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Alzheimer’s: A Biological Model of Prevention – Finally! (Part 1)

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